Background：This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：ASGP-R 1,ASGPR 1,ASGPR,ASGPR1,Asgr1,ASGR1,Asialoglycoprotein receptor 1,C type lectin domain family 4 member H1,C-type lectin domain family 4 member H1,CLEC4H1,Hepatic lectin H1,HL-1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human ASGR1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：1000 - 1：4000 IHC1：50 - 1：200
Gene_ID（human）：432
Swissprot：P07306
Isotype：IgG
Research Areas：Cancer, Signal transduction, Tags ＆ Cell Markers
