Background：This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.
仕様
Synonyms：15 LO 2,15 LOX 2,15-lipoxygenase 2,15-LOX-2,15-LOX-B,Alox15b,Arachidonate 15 lipoxygenase second type,Arachidonate 15 lipoxygenase type II,Arachidonate 15-lipoxygenase B,Arachidonate 15-lipoxygenase type II,LX15B
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human ALOX15B
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：50 - 1：100
Gene_ID（human）：247
Swissprot：O15296
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
