Background：This gene encodes a member of the activator 1 small subunits family. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins, proliferating cell nuclear antigen （PCNA） and replication factor C （RFC）. Replication factor C, also called activator 1, is a protein complex consisting of five distinct subunits. This gene encodes the 40 kD subunit, which has been shown to be responsible for binding ATP and may help promote cell survival. Disruption of this gene is associated with Williams syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene of this gene has been defined on chromosome 2.
仕様
Synonyms：A1 40 kDa subunit,A1,Activator 1 40 kDa subunit,Activator 1,Activator 1 subunit 2,MGC3665,OTTHUMP00000160645,OTTHUMP00000160646,Replication factor C （activator 1） 2 40kDa,Replication factor C （activator 1） 2,Replication factor C 2,Replication factor C 40 kDa subunit,Replication factor C subunit 2,RF C 40 kDa subunit,RF-C 40 kDa subunit,RFC 2,RFC 40,RFC 40 kDa subunit,RFC2,RFC2,RFC40
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human RFC2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：5982
Swissprot：P35250
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
