Background：The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates multiple transcript variants.
仕様
Synonyms：ACS 4,ACS4,ACSL 4,Acsl4,ACSL4,acyl CoA synthetase 4,Acyl CoA synthetase long chain family member 4,FACL 4,FACL4,Fatty acid Coenzyme A ligase,fatty acid Coenzyme A ligase long-chain 4,LACS 4,LACS4,Lignoceroyl CoA synthase,Long chain 4,long chain acyl CoA synthetase 4,long chain fatty acid CoA ligase 4,long chain fatty acid Coenzyme A ligase 4,Long-chain acyl-CoA synthetase 4,Long-chain-fatty-acid--CoA ligase 4,MRX63,MRX68
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ACSL4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：2182
Swissprot：O60488
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
