Background：This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.
仕様
Synonyms：1110014C03Rik ,21 kDa transmembrane trafficking protein,21 kDa transmembrane-trafficking protein,MGC102351,p23,p24 family protein delta 1,p24 family protein delta-1,p24（DELTA）,p24delta,p24delta1,S31I125,S31III125,TMED 10,Tmed10,TMEDA,Tmp 21 I,Tmp 21,Tmp 21 I,Tmp-21-I,Transmembrane emp24 domain containing protein 10,Transmembrane emp24 domain-containing protein 10,Transmembrane emp24-like trafficking protein 10 （yeast）,Transmembrane protein Tmp21,Transmembrane trafficking protein 21kD
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TMED10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
