Background:Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms:RNA polymerase I-specific TBP-associated factor 110 kDa,SL1,Taf1c,TAF1C,TAFI110,TAFI95,TATA box binding protein associated factor 1C,TATA box-binding protein-associated factor 1C,TATA box-binding protein-associated factor RNA polymerase I subunit C,TBP associated factor 1C,TBP associated factor RNA polymerase I 95 kDa,TBP associated factor, RNA polymerase I, 110-KD,TBP-associated factor 1C,Transcription initiation factor SL1/TIF-IB subunit C
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human TAF1C
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.