Background：This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：Histone lysine N methyltransferase,Histone lysine N methyltransferase SETMAR,Hsmar 1,Hsmar1,Mariner transposase Hsmar1,Metnase,SET domain and mariner transposase fusion,SET domain and mariner transposase fusion gene,SET domain and mariner transposase fusion gene containing protein,SET domain and mariner transposase fusion gene-containing protein,Setmar,SETMR
Host：Rabbit
Reactivity：Human
Applications：IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human SETMAR
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
