Background:This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol.
仕様
Synonyms:Annexin A2 like,EC 1 8 4,HSPC 270,HSPC270,Methionine R sulfoxide reductase,Methionine R sulfoxide reductase B1,Methionine sulfoxide reductase,Methionine-R-sulfoxide reductase B1,MGC3344,MSRB 1,MsrB1,MSRB1,OTTHUMP00000159418,Sel X,Selenoprotein R,Selenoprotein X 1,Selenoprotein X,Selenoprotein X1,SELR,SelX,SEPX 1,sepx1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human MSRB1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:100
Gene_ID(human):51734
Swissprot:Q9NZV6
Isotype:IgG
Research Areas:Cancer, Cell Biology, Metabolism, Signal transduction