Background：The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence （SECIS）, a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
仕様
Synonyms：DKFZp686C09169,OTTHUMP00000064929,OTTHUMP00000064930,OTTHUMP00000064931,OTTHUMP00000064932,RP11 89K14.1,SBP 2,SBP2,SEBP2,SECIS binding protein 2,SECIS-binding protein 2,SECISBP 2,SECISBP2,Selenocysteine insertion sequence binding protein 2,Selenocysteine insertion sequence-binding protein 2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human SECISBP2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
