Background:The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anchored glycoprotein may serve as a negative regulator for matrix metalloproteinase-9, a key enzyme involved in tumor invasion and metastasis. Several transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:hRECK,Membrane anchored glycoprotein (metastasis and invasion),RECK,RECK protein,RECK,Reversion inducing cysteine rich protein with Kazal motifs ,Reversion-inducing cysteine-rich protein with Kazal motifs,ST15 ,Suppression of tumorigenicity 15 (reversion inducing cysteine rich protein with kazal motifs),Suppressor of tumorigenicity 15,Suppressor of tumorigenicity 15 protein
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human RECK
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.