Background：Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly（A）-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
仕様
Synonyms：dJ481F12.3,dJ800J21.1,FLJ30608,Homolog of yeast Rae1 （Bharathi） mRNA associated protein of 41 kDa （Kraemer）,Homolog of yeast Rae1 mRNA associated protein of 41 kDa,MGC117333,MGC126076,MGC126077,MIG 14,MIG14,Migration inducing gene 14,Mnrp 41,Mnrp41,mRNA associated protein mrnp 41,mRNA binding protein 41 kD,mRNA export factor,mRNA export protein,mRNA-associated protein mrnp 41,MRNP 41,MRNP41,RAE 1,RAE1 （RNA export 1 S.pombe） homolog,rae1,RAE1 homolog,Rae1 protein homolog,RAE1 RNA export 1 homolog （S. pombe）,RAE1 RNA export 1 homolog,RAE1L,RNA export 1,RNA export 1 homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human RAE1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
