Background：This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element （FUSE） and FUSE-binding protein at the myelocytomatosis oncogene （MYC） promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：60 kDa poly（U）-binding-splicing factor,FBP-interacting repressor,FIR,FLJ31379,FUSE-binding protein-interacting repressor,Poly U binding splicing factor 60KDa,Poly（U） binding splicing factor 60,Poly（U）-binding-splicing factor PUF60,poly-U binding splicing factor PUF60,PUF60,PUF60,pyrimidine tract binding splicing factor ,Ro ribonucleoprotein-binding protein 1,Ro-binding protein 1,RoBP1,RoBPI,siah binding protein 1,Siah-binding protein 1,Siah-BP1,SIAHBP1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,IF,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human PUF60
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
