Background：This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
仕様
Synonyms：L isoaspartyl protein carboxyl methyltransferase,L isoaspartyl/D aspartyl methyltransferase,L-isoaspartyl protein carboxyl methyltransferase,PCMT 1,Pcmt1,PIMT,PIMT,Protein beta aspartate methyltransferase,Protein L isoaspartate （D aspartate） O methyltransferase,Protein L isoaspartyl/D aspartyl methyltransferase,Protein L-isoaspartyl/D-aspartyl methyltransferase,Protein-beta-aspartate methyltransferase,Protein-L-isoaspartate（D-aspartate） O-methyltransferase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human PCMT1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
