Background：This gene encodes a protein that belongs to the Kruppel family of transcription factors. The encoded zinc finger protein is required for normal development of the barrier function of skin. The encoded protein is thought to control the G1-to-S transition of the cell cycle following DNA damage by mediating the tumor suppressor gene p53. Mice lacking this gene have a normal appearance but lose weight rapidly, and die shortly after birth due to fluid evaporation resulting from compromised epidermal barrier function. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：Endothelial Kruppel like zinc finger protein ,Epithelial zinc finger protein EZF,EZF,GKLF,gut Kruppel-like factor,Gut-enriched krueppel-like factor,KLF,KLF4,KLF4,Krueppel-like factor 4,Kruppel like factor 4 （Epithelial zinc finger protein EZF） （Gut enriched Krueppel like factor）,Kruppel like factor 4 （gut）
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human KLF4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：9314
Swissprot：O43474
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells
