Background：Voltage-gated potassium （Kv） channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming （alpha） subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
仕様
Synonyms：EAG,EAG channel 1,EAG1,Ether a go go potassium channel 1,Ether a go go,Drosophila,homolog of,Ether-a-go-go potassium channel 1,ether-a-go-go,Drosophila,homolog of,h eag,h-eag,hEAG1,Kcnh1,KCNH1,Kv10.1,M eag,MGC124419,MGC124420,MGC142269,Potassium voltage gated channel subfamily H （eag related）,member 1,Potassium voltage gated channel subfamily H member 1,Potassium voltage-gated channel subfamily H member 1,Voltage gated potassium channel subunit Kv10.1,Voltage-gated potassium channel subunit Kv10.1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human KCNH1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
