Background：The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix （HLH） motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.
仕様
Synonyms：GTF2IRD1,CREAM1,GTF3,MUSTRD1,RBAP2,WBSCR11,WBSCR12,General transcription factor II-I repeat domain-containing protein 1,GTF2I repeat domain-containing protein 1,General transcription factor III,MusTRD1/BEN,Muscle TFII-I repeat do
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human GTF2IRD1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
