Background：This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta （TGF-beta） family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis.
仕様
Synonyms：BAMBI,BAMBI,BMP and activin membrane bound inhibitor homolog,BMP and activin membrane-bound inhibitor homolog,NMA,Non metastatic gene A protein,Non-metastatic gene A protein,Putative transmembrane protein NMA
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human BAMBI
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
