Background：This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60％ identical at the amino acid level to conventional actin.
仕様
Synonyms：Actin related protein 1,Actin RPV,Actin-RPV,ACTR 1A,Actr1a,ACTZ,Alpha centractin,Alpha-centractin,ARP 1,ARP1 actin related protein 1 homolog A,ARP1 actin related protein 1 homolog A centractin alpha,ARP1,ARP1 yeast homolog A,Centractin alpha,Centractin,Centrosome associated actin homolog,Centrosome-associated actin homolog,CTRN 1,CTRN1,FLJ52695,FLJ52800,FLJ55002
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ACTR1A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
