Background:The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
仕様
Synonyms:C4orf5,Calcineurin binding protein calsarcin 1,Calsarcin 1,Calsarcin-1,Calsarcin1,CMH16,CS 1,CS1,FATZ related protein 2,FATZ-related protein 2,Muscle specific protein,MYOZ 2,MYOZ2,MYOZ2,Myozenin-2,Myozenin2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human MYOZ2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:50 - 1:100
Gene_ID(human):51778
Swissprot:Q9NPC6
Isotype:IgG
Research Areas:Cardiovascular, Signal transduction