Background：The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：95 kDa retinoblastoma associated protein,95 kDa retinoblastoma protein binding protein,95 kDa retinoblastoma-associated protein,BRE 1B,BRE1 B,BRE1 E3 ubiquitin ligase homolog B,BRE1-B,BRE1B,BRE1B,DKFZp686K191,E3 ubiquitin protein ligase BRE1B,E3 ubiquitin-protein ligase BRE1B,KIAA0661,MGC13051,Rb associated protein,RBP 95,RBP95,RING finger protein 40,Ring finger protein 40 E3 ubiquitin protein ligase,RNF 40,Rnf40,STARING
Host：Rabbit
Reactivity：Human
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human RNF40
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
