Background：Cytochrome c oxidase （COX） is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.
仕様
Synonyms：COX,COX VA,COX5A,COX5A,Cytochrome c oxidase polypeptide Va,Cytochrome c oxidase polypeptide,mitochondrial,Cytochrome c oxidase subunit 5A,Cytochrome c oxidase subunit 5A,mitochondrial,Cytochrome c oxidase subunit Va,mitochondrial,Mitochondrial cytochrome c oxidase subunit Va,VA
