Background：The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor （I alpha I）, and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
仕様
Synonyms：Hyaluronate binding protein,Hyaluronate-binding protein,TNF alpha induced protein 6,TNF alpha-induced protein 6,TNF stimulated gene 6 protein,TNF-stimulated gene 6 protein,TNFAIP 6,Tnfaip6,TSG 6,TSG-6,TSG6,Tumor necrosis factor alpha induced protein 6,Tumor necrosis factor alpha inducible protein 6,Tumor necrosis factor alpha-induced protein 6,Tumor necrosis factor inducible gene 6 protein,Tumor necrosis factor stimulated gene 6 protein,Tumor necrosis factor-inducible gene 6 protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TNFAIP6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：7130
Swissprot：P98066
Isotype：IgG
Research Areas：Cancer, Immunology, Signal transduction
