Background:This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Early growth response, alpha,Early growth response, alpha like,EGR A,EGR alpha ,EGR(A),EGR-alpha,EGRA,Egral,EGRalpha,Gdnfif,KLF 10,KLF10,KLF10,Krueppel like factor 10,Krueppel like factor10,Krueppel-like factor 10,Kruppel like factor 10,mGIF,TGF-beta- inducible early gene,TGFB inducible early growth response 1,TGFB inducible early growth response,TGFB inducible early growth response protein 1,TGFB-inducible early growth response protein 1,TIEG 1,TIEG,TIEG-1,TIEG1,Transforming growth factor beta inducible early growth response,Transforming growth factor beta inducible early growth response protein 1,Transforming growth factor-beta-inducible early growth response protein 1,Zinc finger transcription factor TIEG
Host:Rabbit
Reactivity:Human
Applications:IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human KLF10
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:IF1:50 - 1:100
Gene_ID(human):7071
Swissprot:Q13118
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Signal transduction