Background：The protein encoded by this gene is a member of the protein tyrosine phosphatase （PTP） family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：cytoskeletal-associated protein tyrosine phosphatase,protein tyrosine phosphatase H1,protein tyrosine phosphatase non-receptor type 3,Protein-tyrosine phosphatase H1,PTN3,PTP-H1,PTPH1,PTPN3,Tyrosine-protein phosphatase non-receptor type 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PTPN3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
