Background:Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
仕様
Synonyms:Breast normal epithelial cell associated serine protease,Kallikrein related peptidase 10,Kallikrein-10,Kallikrein10,KLK 10,KLK10,KLK10,NES 1,NES1,Normal epithelial cell specific 1,Normal epithelial cell-specific 1,Protease serine like 1,Protease serine-like 1,PRSS L1,PRSSL 1,PRSSL1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human KLK10
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Gene_ID(human):5655
Swissprot:O43240
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction