Background： Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists （types I and II） which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
仕様
Synonyms：ARG2,ARGI2,Arginase II mitochondrial,Arginase type II,Arginase-2,arginase-2,mitochondrial,Kidney arginase,Kidney type arginase,Kidney-type arginase,L arginine amidinohydrolase,L arginine ureahydrolase,mitochondrial,Non hepatic arginase,Non-hepatic arginase,Nonhepatic arginase,Type II arginase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ARG2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：384
Swissprot：P78540
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
