Background:This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:3 alpha hydroxysteroid dehydrogenase,3-@alpha-HSD,3-@alpha-hydroxysteroid dehydrogenase,3-alpha hydroxysteroid dehydrogenase,3-alpha-HSD,3alpha HSD,Dehydrogenase/reductase SDR family member 9,DHRS9,DHRS9,NADP dependent retinol dehydrogenase/reductase,NADP-dependent retinol dehydrogenase/reductase,RDH-E2,Rdh15,RDHE2,RDHL,RDHTBE,retinol dehydrogenase homolog ,Retinol dehydrogenase, tracheobronchiol epithelail cell-specific,RETSDR8,SDR family, member 9,SDR9C4,short chain dehydrogenase/reductase family 9,short chain dehydrogenase/reductase family 9C, member 4 ,Short chain dehydrogenase/reductase retSDR8,Short-chain dehydrogenase/reductase retSDR8
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human DHRS9
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.