Background:The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene.
仕様
Synonyms:ACACT,ACAT,ACAT-1,ACAT1,Acyl coenzyme A cholesterol acyltransferase 1,Acyl-coenzyme A:cholesterol acyltransferase 1,Cholesterol acyltransferase 1,SOAT,SOAT1,SOAT1,STAT,Sterol O acyltransferase 1,Sterol O-acyltransferase 1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human SOAT1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):6646
Swissprot:P35610
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction