Background：This gene encodes the prototype of the membrane-associated guanylate kinase （MAGUK） family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 （SH3） motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：55 kDa erythrocyte membrane protein,AAG 12,AAG12,Aging associated gene 12,DXS552,DXS552E,EM55,EMP 55,EMP55,Erythrocyte membrane protein p55,Membrane protein,Membrane protein palmitoylated 1 55kDa,Membrane protein palmitoylated 1,Membrane protein, palmitoylated 1, 55kDa,Migration related gene 1,MPP 1,MPP1,MRG 1,MRG1,OTTHUMP00000026054,OTTHUMP00000196176,p55,palmitoylated 1,Palmitoylated erythrocyte membrane protein,Palmitoylated membrane protein 1,PEMP
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human MPP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4354
Swissprot：Q00013
Isotype：IgG
Research Areas：Cardiovascular, Signal transduction
