Background:This gene encodes a protein that belongs to the pro-apoptotic subfamily within the Bcl-2 family of proteins. The encoded protein binds to Bcl-2 and possesses the BH3 domain. The protein directly targets mitochondria and causes apoptotic changes, including loss of membrane potential and the release of cytochrome c.
仕様
Synonyms:Adenovirus E1B19k binding protein B5,Adenovirus E1B19K-binding protein B5,BCL2/adenovirus E1B 19 kd protein interacting protein 3a,BCL2/adenovirus E1B 19 kDa protein interacting protein 3A,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like,BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A,BCL2/adenovirus E1B 19kDa interacting protein 3 like,BNI3L,BNIP3a,BNIP3H,BNIP3L,BNIP3L protein,NIP3 like protein X,NIP3-like protein X,NIP3L,NIX
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human BNIP3L
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):665
Swissprot:O60238
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular, Metabolism