Background：The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand （TNFSF10/TRAIL）, and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
仕様
Synonyms：Apo2,CD261,Cytotoxic TRAIL receptor,Death receptor 4,DR4,NF related apoptosis-inducing ligand receptor 1,TNF receptor superfamily member 10a,TNF-related apoptosis-inducing ligand receptor 1,TNFRSF10A,TR10A,TRAIL receptor 1,TRAIL-R1,TRAILR 1,TRAILR1,Tumor necrosis factor receptor superfamily member 10A,Tumor necrosis factor receptor superfamily member 10a variant 2,Tumor necrosis factor receptor superfamily,member 10a
Host：Rabbit
Reactivity：Human
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human TNFRSF10A
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：200 - 1：500 IHC1：50 - 1：100
Gene_ID（human）：8797
Swissprot：O00220
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Immunology
