Background:The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Anti elastase,EI,ELANH2,Epididymis luminal protein 57,HEL57,ILEU,LEI,Leukocyte elastase inhibitor,M/NEI,MNEI,Monocyte/neutrophil elastase inhibitor,Peptidase inhibitor 2,Pi-2,PI2,Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 1,Serpin B1,Serpin peptidase inhibitor clade B (ovalbumin) member 1,serpinb1
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human SERPINB1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IF1:20 - 1:100
Gene_ID(human):1992
Swissprot:P30740
Isotype:IgG
Research Areas:Cancer, Cell Biology, Cardiovascular