Background:This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:Brefeldin A sensitive peripheral Golgi protein,CDG2Q,COG 2,COG complex subunit 2,COG2,COG2,Component of oligomeric Golgi complex 2,Conserved oligomeric Golgi complex component 2,Conserved oligomeric Golgi complex subunit 2,LDLC,Low density lipoprotein receptor defect C complementing protein,Low density lipoprotein receptor defect C-complementing protein,Transcript ch4822
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:Recombinant protein of human COG2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000 IHC1:50 - 1:200
Gene_ID(human):22796
Swissprot:Q14746
Isotype:IgG
Research Areas:Cancer, Signal transduction, Tags & Cell Markers