Background：The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
仕様
Synonyms：CD49 antigen-like family member E,CD49e,Fibronectin receptor subunit alpha,Fibronectin receptor,alpha subunit,FNRA,Integrin alpha 5 （fibronectin receptor alpha）,Integrin alpha-5,Integrin alpha-5 light chain,Integrin alpha-F,Integrin,alpha 5 （fibronectin receptor,alpha polypeptide）,ITA5,Itga5,Very late activation protein 5,alpha subunit,VLA-5,VLA5,VLA5A
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human ITGA5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：3678
Swissprot：P08648
Isotype：IgG
Research Areas：Cancer, Signal transduction, Stem cells
