Background：Voltage-gated potassium （Kv） channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog（s）. This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as it is in Shaker channels.
仕様
Synonyms：KCD2,KCND 2,KCND2,KCND2,KIAA1044,MGC119702,MGC119703,Potassium voltage gated channel Shal related subfamily member 2,Potassium voltage-gated channel subfamily D member 2,RK 5,RK5,Voltage gated potassium channel Kv4.2,Voltage gated potassium channel subunit Kv4.2,Voltage sensitive potassium channel,Voltage-gated potassium channel subunit Kv4.2
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human KCND2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：3751
Swissprot：Q9NZV8
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience
