Background：This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly（C） as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
仕様
Synonyms：HP-RNase,Pancreatic ribonuclease,Rib 1,RIB-1,Rib1,Ribonuclease 1,Ribonuclease A,Ribonuclease a family 1,Ribonuclease pancreatic,Ribonuclease RNase A family 1,Ribonuclease RNase A family 1 pancreatic,RNAS1,RNase 1,RNase A,RNase UpI-1,Rnase1,RNAseA
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human RNASE1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：6035
Swissprot：P07998
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
