Background：CCCTC-binding factor （CTCF）, an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：BORIS like protein,Brother of the regulator of imprinted sites,Cancer/testis antigen 27,CCCTC binding factor （zinc finger protein） like,CCCTC-binding factor,CT27,CTCF paralog,CTCF T,CTCF-like protein,Ctcfl,CTCFL,dJ579F20.2,HMG 1L1,HMGB1L1,MGC163358,MGC169105,MGC169106,Putative high mobility group protein 1 like 1,Putative high mobility group protein B1 like 1,Transcriptional repressor CTCFL,Zinc finger protein CTCF-T
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IF
Concentration：1mg/ml
Immunogen：Recombinant protein of human CTCFL
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IF1：20 - 1：100
Gene_ID（human）：140690
Swissprot：Q8NI51
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
