Background：This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.
仕様
Synonyms：AU022152,EC 2.1.1.43,ERG-associated protein with SET domain,ESET,H3 K9 HMTase 4,H3-K9-HMTase 4,H3-K9-HMTase4,Histone H3 K9 methyltransferase 4,Histone H3-K9 methyltransferase 4,Histone-lysine N-methyltransferase SETDB1,KG1T,KIAA0067,KMT1E,Lysine N-methyltransferase 1E,MGC90670,mKIAA0067,SET domain bifurcated 1,Set domain protein,bifurcated,1,SETB1,Setdb1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human SETDB1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：9869
Swissprot：Q15047
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
