Background:This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. Alternate transcriptional splice variants have been characterized.
仕様
Synonyms:HDCMC04P,Histone lysine N methyltransferase MLL5,Histone-lysine N-methyltransferase MLL5,KMT2E,Lysine N methyltransferase 2E ,Lysine N-methyltransferase 2E,MGC70452,Mll5,MLL5,Myeloid/lymphoid or mixed lineage leukemia 5 (trithorax homolog, Drosophila),Myeloid/lymphoid or mixed lineage leukemia 5,Myeloid/lymphoid or mixed lineage leukemia protein 5,Myeloid/lymphoid or mixed-lineage leukemia protein 5
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human KMT2E
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Dilution:WB1:500 - 1:2000 IF1:50 - 1:200
Gene_ID(human):55904
Swissprot:Q8IZD2
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Developmental biology, Stem cells