Background:This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing.
仕様
Synonyms:CAG repeat protein 26,CAGH26,DKFZp666E117,EDIE ,EMSY interactor protein,FLJ22043,Glycine tryptophan protein of 182 kDa,Glycine-tryptophan protein of 182 kDa,GW1,GW182,GW182 autoantigen,Hypothetical protein DKFZp566M143 ,KIAA1460,MGC75384,OTTHUMP00000122485,OTTHUMP00000195164,OTTHUMP00000195165,Protein GW1,TNR6A,TNRC 6A,TNRC6,Tnrc6a,Trinucleotide repeat containing 6A,Trinucleotide repeat containing gene 6A protein,Trinucleotide repeat-containing gene 6A protein
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB
Concentration:1mg/ml
Immunogen:A synthetic peptide of human TNRC6A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:1000
Gene_ID(human):27327
Swissprot:Q8NDV7
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling