Background：The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
仕様
Synonyms：Cancer/testis antigen 98,CT98,DKFZp686F1078,hKOC,IF2B3,IGF II mRNA binding protein 3,IGF-II mRNA-binding protein 3,IGF2 mRNA binding protein 3,IGF2 mRNA-binding protein 3,IGF2BP3,IMP 3,IMP-3,Insulin like growth factor 2 mRNA binding protein 3,Insulin-like growth factor 2 mRNA-binding protein 3,KH domain containing protein overexpressed in cancer,KH domain-containing protein overexpressed in cancer,KOC 1,KOC1,VICKZ 3,VICKZ family member 3,VICKZ3
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IP
Concentration：1mg/ml
Immunogen：Recombinant protein of human IGF2BP3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Dilution：WB1：500 - 1：1000 IP1：20 - 1：50
Gene_ID（human）：10643
Swissprot：O00425
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
