Background:A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms:ELAV (embryonic lethal abnormal vision Drosophila) like 3 (Hu antigen C),ELAV like protein 3,ELAV-like protein 3,ELAV3,Elavl3,Embryonic lethal,abnormal vision,drosophila,homolog-like,Hu antigen C,Hu-antigen C,HuC,HUCL,MGC20653,Paraneoplastic cerebellar degeneration associated antigen,Paraneoplastic cerebellar degeneration-associated antigen,Paraneoplastic limbic encephalitis antigen 21,PLE21
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC
Concentration:1mg/ml
Immunogen:A synthetic peptide of human ELAVL3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:1000 IHC1:50 - 1:200
Gene_ID(human):1995
Swissprot:Q14576
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Neuroscience