Background:The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.
仕様
Synonyms:Aging associated gene 7 protein,Nucleolysin TIAR,T cluster binding protein,TCBP,TIA 1 related nucleolysin,TIA-1-related protein,TIA1 cytotoxic granule associated RNA binding protein like 1,TIA1 related protein,TIAL1,TIAR,TIAR
Host:Rabbit
Reactivity:Human
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant Protein of human TIAL1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB1:500 - 1:2000
Gene_ID(human):7073
Swissprot:Q01085
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling