Background：Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif （RRM） domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 （DM1） via interactions with the dystrophia myotonica-protein kinase （DMPK） gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
仕様
Synonyms：50 kDa Nuclear polyadenylated RNA binding protein,50 kDa nuclear polyadenylated RNA-binding protein,Bruno like 2,bruno like protein 2,Bruno-like protein 2,BRUNOL 2,BRUNOL2,CELF 1,CELF-1,celf1,CELF1 CUGBP,Elav like family member 1,CELF1,CUG BP and ETR 3 like factor 1,CUG BP,CUG BP1,CUG RNA binding protein,CUG triplet repeat RNA binding protein 1,CUG triplet repeat RNA-binding protein 1,CUG-BP,CUG-BP- and ETR-3-like factor 1,CUG-BP1,CUGBP 1,CUGBP and ETR3 like factor 1,CUGBP,CUGBP Elav like family member 1,CUGBP Elav-like family member 1,CUGBP1,Cytidine uridine guanosine binding protein 1,Deadenylation factor CUG BP,Deadenylation factor CUG-BP,Deadenylation factor CUGBP,EDEN BP,EDEN BP homolog,EDEN-BP,EDEN-BP homolog,embryo deadenylation element binding protein,embryo deadenylation element binding protein homolog,Embryo deadenylation element-binding protein homolog,hNab 50,hNab50,NAB 50,NAB50,NAPOR,Nuclear polyadenylated RNA binding protein 50 kD,Nuclear polyadenylated RNA binding protein,RNA binding protein BRUNOL 2,RNA binding protein BRUNOL2,RNA-binding protein BRUNOL-2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human CELF1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：200 - 1：2000
Gene_ID（human）：10658
Swissprot：Q92879
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Neuroscience
