Background：Protein kinase C （PKC） is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor （TCR） signaling complex to the activation of the transcription factors.
仕様
Synonyms：KPCT,MGC126514,MGC141919,nPKC theta,nPKC-theta,nPKCtheta,OTTHUMP00000043364,OTTHUMP00000043365,PKC 0,PKC0,Prkcq,PRKCT,Protein kinase C theta,Protein kinase C theta type,Protein Kinase Ctheta
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC
Concentration：1mg/ml
Immunogen：Recombinant protein of human PRKCQ
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000 IHC1：50 - 1：200
Gene_ID（human）：5588
Swissprot：Q04759
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
