Background：This gene encodes a member of the family of NGFI-A binding （NAB） proteins, which function in the nucleus to repress transcription induced by some members of the EGR （early growth response） family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase （NuRD） complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
仕様
Synonyms：EGR 1 binding protein 2,EGR-1-binding protein 2,EGR1 binding protein 2,MADER,Melanoma associated delayed early response protein,Melanoma-associated delayed early response protein,MGC75085,Nab 2,nab2,NAB2,NGFI A binding protein 2 （EGR1 binding protein 2）,NGFI A binding protein 2,NGFI-A-binding protein 2,Protein MADER
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human NAB2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
Dilution：WB1：500 - 1：2000
Gene_ID（human）：4665
Swissprot：Q15742
Isotype：IgG
Research Areas：Epigenetics and Nuclear Signaling, Neuroscience
