Background：This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仕様
Synonyms：DIAPH1,deafness, autosomal dominant 1,DFNA1,DIA1,DIAP1,DIAP1,DIAPH1,Diaphanous homolog 1 （Drosophila）,diaphanous homolog 1,Diaphanous related formin 1,Diaphanous-related formin-1,DRF1,FLJ25265,hDIA1,LFHL1,low frequency hearing loss 1,p140DIA,Protein diaphanous homolog 1
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human DIAPH1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
