Background:The protein encoded by this gene contains a RING finger motif, which is most closely related to those of polycomb group (PcG) proteins RNF110/MEL-18 and BMI1. PcG proteins are known to form protein complexes and function as transcription repressors. This protein has been shown to interact with some PcG proteins and act as a transcription repressor. The activity of this protein is found to be regulated by cell cycle dependent phosphorylation. Alternatively spliced transcript variants encoding different isoforms have been identified.
仕様
Synonyms:MBLR,Mel18 and Bmi1 like RING finger protein,Mel18 and Bmi1-like RING finger,Pcgf6,PCGF6,Polycomb group RING finger protein 6,RING finger protein 134,RNF134
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IF
Concentration:1mg/ml
Immunogen:Recombinant protein of human PCGF6
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.