Background:This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:D22S676,D22S750,II,Macrocytic anemia,OTTHUMP00000199117,OTTHUMP00000199118,OTTHUMP00000199119,TC,TC II,TC II deficiency,TC-2,TC2,TCII,TCN2,TCN2 deficiency,TCO2,Transcobalamin 2,Transcobalamin 2 deficiency,Transcobalamin II,Transcobalamin II,macrocytic anemia,Transcobalamin-2,Vitamin B12 binding protein 2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB
Concentration:1mg/ml
Immunogen:Recombinant protein of human TCN2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Dilution:WB 1:500 - 1:2000
Gene_ID(human):6948
Swissprot:P20062
Isotype:IgG
Research Areas:Cardiovascular, Metabolism, Signal transduction