Background：This gene encodes a member of the inhibitor of apoptosis protein （IAP） family, and contains a single copy of a baculovirus IAP repeat （BIR） as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants
仕様
Synonyms：Baculoviral IAP repeat containing 7,Baculoviral IAP repeat containing protein 7,Baculoviral IAP repeat-containing protein 7,BIRC 7,birc7,BIRC7,KIAP,Kidney inhibitor of apoptosis protein,Livin,Livin inhibitor of apotosis,Melanoma inhibitor of apoptosis protein,ML IAP,ML-IAP,MLIAP,RING finger protein 50,RNF 50,RNF50
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB
Concentration：1mg/ml
Immunogen：Recombinant protein of human BIRC7
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：Buffer： PBS with 0.02％ sodium azide, 50％ glycerol, pH7.3.
